Wharton’s Jelly – Commonly referred to as Human Cellular Tissue Product by the FDA and their governing agencies, Wharton’s Jelly Wharton’s jelly, a gelatinous substance found in the umbilical cord, has emerged as a promising source of mesenchymal stem cells (MSCs) for regenerative medicine applications in orthopedic surgery and other compounds that help with healthy tissue repair, making them particularly valuable for treating musculoskeletal conditions[1][2].
Research has shown potential applications of Wharton’s jelly-derived stem cells in treating cartilage injuries, degenerative disc disease, osteoporotic vertebral compression fractures, and osteoarthritis. In animal studies, injection of Wharton’s jelly cells into degenerated intervertebral discs resulted in slower progression of disc height loss and improved disc health compared to controls[2].
The use of Wharton’s jelly for orthopedic applications offers several advantages over other stem cell sources. It is easily accessible and available from every birth, without the donor site morbidity associated with bone marrow or adipose-derived stem cell harvesting. The cells from Wharton’s jelly also have attractive expansion properties and contain clinically significant amounts of regenerative substances[1],
Sources
[1] Umbilical cord-derived Wharton’s jelly for regenerative medicine … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659052/
[2] Umbilical Cord-Derived Wharton’s Jelly for Regenerative Medicine … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618385/
[3] Wharton Jelly – an overview | ScienceDirect Topics https://www.sciencedirect.com/topics/medicine-and-dentistry/wharton-jelly
[4] (PDF) Umbilical cord-derived Wharton’s Jelly for Regenerative … https://www.researchgate.net/publication/346592311_Umbilical_cord-derived_Wharton%27s_Jelly_for_Regenerative_Medicine_Applications_in_Orthopedic_Surgery_A_Systematic_Review_Protocol
[5] Wharton’s Jelly Injections for Knee Pain, Arthritis, Tendonitis & More https://axeholisticmedicine.com/whartons-jelly-injections/